Case-control study of obstetrical outcomes of conisation

Journal de gynécologie, obstétrique et biologie de la reproduction
C BrieM Dreyfus

Abstract

Evaluate the obstetrical outcomes in the case of women with a history of conization. Determine the role of the cone length in the obstetrical issue. Retrospective case-control study including the patients (n=39) who had undergone a conization in a university hospital between January 2002 and January 2012. The obstetrical outcomes have been compared to those from a control group (n=78). Into the exposed group the obstetrical outcomes has been compared based on the cone length. Thirty-one patients delivered after a conization (39 deliveries). The obstetrical outcomes have been significantly increased in the exposed group: preterm delivery before 37 weeks gestation (25.6% vs 7.7%, P=0.01), before 32 weeks gestation (15.4% vs 1.3%, P=0.005) and between 28 weeks gestation (10.2% vs 0%, P=0.01), premature onset of labor before 32 weeks gestation (12.8% vs 1.3%, P=0.01) and before 28 weeks gestation (12.8% vs 0%, P=0.01) and preterm premature rupture of membranes before 37 weeks gestation (20.5% vs 1.3%, P<0.001). There was no significant difference for a length cone more than 1.5cm. Our study showed that a history of conization is an obstetrical risk factor to consider in the management of a subsequent pregnancy.

References

May 6, 2004·JAMA : the Journal of the American Medical Association·Lynn SadlerLesley McCowan
Dec 24, 2008·Obstetrics and Gynecology·Philip E CastleDiane Solomon
Feb 28, 2009·Gynécologie, obstétrique & fertilité·J Marchetta
Aug 25, 2009·Obstetrics and Gynecology·Maija JakobssonAnna-Maija Tapper
Dec 1, 2009·BJOG : an International Journal of Obstetrics and Gynaecology·G OrtoftLk Petersen
Dec 1, 2009·BJOG : an International Journal of Obstetrics and Gynaecology·A van de VijverM Arbyn
Apr 1, 2011·BJOG : an International Journal of Obstetrics and Gynaecology·F J Bruinsma, M A Quinn
Feb 15, 2012·BJOG : an International Journal of Obstetrics and Gynaecology·S KhalidW Prendiville
Feb 22, 2012·Reproduction : the Official Journal of the Society for the Study of Fertility·Mala Mahendroo
Jul 19, 2012·BJOG : an International Journal of Obstetrics and Gynaecology·C SimoensM Arbyn
Jul 3, 2013·Journal de gynécologie, obstétrique et biologie de la reproduction·J-J BaldaufC Y Akladios

❮ Previous
Next ❯

Citations

Nov 3, 2017·The Cochrane Database of Systematic Reviews·Maria KyrgiouEvangelos Paraskevaidis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.