Case-control study on beneficial effect of regular consumption of apples on colorectal cancer risk in a population with relatively low intake of fruits and vegetables

European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)
Wieslaw JedrychowskiAgnieszka Musial

Abstract

Laboratory in-vitro studies and animal experiments showing the potential health benefits from apples raises the question to what extent the regular consumption of apples in humans may have a beneficial effect on colorectal cancer risk. A total of 592 incident cases of colorectal cancer have been enrolled in a hospital-based case-control study. The comparison group included 765 controls chosen from the patients of the same hospital without history of cancer and admitted for treatment of nonneoplastic conditions. Interviews of both cases and controls were conducted in the hospital setting by trained interviewers. The median intake of fruits among cases was lower than in controls (9.5 vs. 11 servings/week) and the difference was statistically significant. Apples were the most frequent fruit consumed by the study participants and about 80% of variability in the total fruit consumption resulted from the intake of apples. We did not observe any significant statistical differences in consumption of berries, citrus, or stone fruits and other kinds of fruits across cases and controls. The adjusted estimates of colorectal cancer risk related to the daily consumption of apples (in quintiles) were based on the unconditional multivariate lo...Continue Reading

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Jun 12, 2012·Current Problems in Surgery·Supriya S PatelAnthony J Senagore
Mar 24, 2016·Public Health Nutrition·Roberto FabianiPatrizia Rosignoli
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Sep 16, 2017·Journal of Food and Drug Analysis·Shih-Hsin TuYuan-Soon Ho

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