PMID: 15220738Jun 29, 2004Paper

Case of a large, movable bacterial concretion with biofilm formation on the ocular surface

Cornea
Etsuko MiharaYoshitsugu Inoue

Abstract

To report a case with a large movable bacterial concretion formed on the ocular surface without biomaterials. Interventional case report. A 74-year-old woman with left eye pain and injection was referred to us. She had a past history of scleral patch graft for necrotizing scleritis after pterygium removal and mitomycin C instillation on her left eye 7 years before. On present examination, a 2.5- to 3.0-mm yellowish-white calcification-like mass was present on the nasal sclera and cornea, and it moved slightly with blinking. The anterior chamber was shallow, and cornea was suspected to be perforated under this object. This yellowish-white mass was surgically removed. Pathologic examination demonstrated that the specimen was not a calcification but a biofilm formation by many gram-positive bacilli with neutrophils. Corynebacterium was highly suspected as the causative agent of this unusual mass because of the earlier culture of the discharge before referral. The current case demonstrates that bacterial biofilms can be formed on the ocular surface without the involvement of biomaterials.

References

Mar 1, 1976·The British Journal of Ophthalmology·P G Watson, S S Hayreh
Jun 1, 1991·Ophthalmology·S P HollandJ W Costerton
Jan 1, 1995·Eye·M J ElderJ K Dart
Jan 1, 1993·Documenta Ophthalmologica. Advances in Ophthalmology·M Sainz de la MazaC S Foster
Apr 16, 1998·The British Journal of Ophthalmology·C H HsiaoR J Tsai
Jan 13, 2000·Cornea·F C HuangS H Tseng

❮ Previous
Next ❯

Citations

Jul 1, 2011·Japanese Journal of Ophthalmology·Akiko FukumotoShigeru Kinoshita
Oct 5, 2007·Journal of Clinical Microbiology·Takashi SuzukiYuichi Ohashi
Mar 14, 2019·Cornea·Andrea CórdobaAlejandro Navas

❮ Previous
Next ❯

Related Concepts

Related Feeds

Biofilm & Infectious Disease

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.

Biofilms

Biofilms are adherent bacterial communities embedded in a polymer matrix and can cause persistent human infections that are highly resistant to antibiotics. Discover the latest research on Biofilms here.