Case of inflammatory vasculopathy and encephalopathy caused by treatment with tacrolimus

Der Nervenarzt
Adrian RingelsteinPeter Berlit

Abstract

The case of inflammatory vasculopathy and encephalopathy caused by treatment with tacrolimus is reported. This 49-year-old woman developed progressive gait ataxia and right-sided hemiparesis after 7 years of tacrolimus therapy for focal sclerosing glomerulonephritis. MRI presented multifocal cerebral lesions with contrast enhancement. Oligoclonal banding was positive. When the treatment with tacrolimus was stopped, the clinical symptoms resolved completely and the MRI findings improved with corticoid monotherapy.

References

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Nov 8, 2001·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·E F Wijdicks
Feb 11, 2004·Der Nervenarzt·P Berlit

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