Case of moyamoya disease in a patient with advanced acquired immunodeficiency syndrome

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
Sophia R SharfsteinVladimir Ratushny

Abstract

Moyamoya disease is an occlusion of the terminal portion of internal carotid arteries and proximal portion of middle and anterior cerebral arteries of unknown origin. Moyamoya syndrome is associated with meningitis, tuberculosis, syphilis, head trauma, head irradiation, brain tumor, von Recklinghausen's disease, tuberous sclerosis, Marfan syndrome, sickle cell anemia, arteriosclerosis, hypertension, and oral contraceptive use. To our knowledge, acquired immunodeficiency syndrome (AIDS) as a cause of moyamoya syndrome has not been reported in an adult population. We report a case of moyamoya syndrome in a patient with AIDS and without other conditions associated with occlusion of the circle of Willis and formation of collateral network at the base of the brain and basal ganglia. We present a case report. A 29-year-old woman with an 8-year history of AIDS on multiple antiretroviral medications presented with recurrent tingling of the left extremities which 1 month later progressed to mild hemiparesis and dysarthria. During the next few months the patient developed progressive cognitive decline and on-and-off fluctuations in the degree of hemiparesis. Brain magnetic resonance imaging showed multiple small subcortical infarct's in ...Continue Reading

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Citations

Dec 29, 2009·Journal of Neurology·Markus Kraemer, Peter Berlit
Aug 3, 2011·Journal of Neurosciences in Rural Practice·Fahmi Yousef KhanAhmed Hayati
Oct 17, 2015·British Journal of Neurosurgery·Pennylouise HeverChristos Tolias
May 11, 2011·Pediatric Neurology·Stuart CurriePaul D Griffiths
Oct 3, 2009·Clinical Neurology and Neurosurgery·V GalatiN Petrosillo
Feb 2, 2013·International Journal of Laboratory Hematology·R AgrawalT I George
Sep 22, 2012·Lancet Neurology·Laura A BenjaminMyles D Connor
Nov 18, 2016·Annals of African Medicine·Ujjawal RoyPrabhat Kumar Lal
Mar 11, 2016·Journal of Child Neurology·Charles K HammondJo M Wilmshurst
Aug 31, 2016·Molecular Medicine Reports·Zhiyou CaiGuanghui Chen
Jul 10, 2019·Neurologia Medico-chirurgica·Takeshi MikamiNobuhiro Mikuni
Dec 1, 2017·The Pediatric Infectious Disease Journal·Ankur Kumar JindalParamjeet Singh
Jan 10, 2020·Developmental Medicine and Child Neurology·Nomazulu DlaminiJo Wilmshurst
Nov 13, 2020·Frontiers in Neurology·Xiaoli SiJiali Pu
Sep 21, 2021·Frontiers in Neurology·Brandon M FoxJohn E Wanebo

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