Case Report: Atrial Fibrillation After Intravenous Administration of Iodinated Contrast Medium in a Patient With Hepatocellular Carcinoma

Medicine
Sergio MaimoneGiovanni Squadrito

Abstract

We describe the case of a 73-year-old woman with liver cirrhosis and hepatocellular carcinoma (HCC) who developed 2 distinct episodes of paroxystic atrial fibrillation (AF) each of which occurred 1 to 4 hours after iodine medium contrast-enhanced computed tomography. Sinus rhythm was restored by amiodarone therapy after the first AF episode and by electrical cardioversion after the second one. A careful clinical, biochemical, and instrumental examination showed that the patient had subclinical hyperthyroidism and moderate mitral insufficiency with mild atrial enlargement.Thus, the coexistence of both subclinical disthyroidism and of cardiac anatomical alterations may have predisposed the patient to AF that in fact occurred when exogenous iodine administration triggered a hyperthyroidism status.

References

Apr 1, 1996·Thyroid : Official Journal of the American Thyroid Association·J J ConnF I Martin
Feb 15, 2001·The New England Journal of Medicine·I Klein, K Ojamaa
May 11, 2001·The New England Journal of Medicine·A L KleinUNKNOWN Assessment of Cardioversion Using Transesophageal Echocardiography Investigators
Mar 5, 2004·European Radiology·Aart J van der MolenUNKNOWN Contrast Media Safety Committee, European Society of Urogenital Radiology (ESUR)
Nov 28, 2006·Endocrinology and Metabolism Clinics of North America·Bindu Nayak, Kenneth Burman
Oct 10, 2007·Circulation·Irwin Klein, Sara Danzi
Mar 5, 2011·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jordi BruixUNKNOWN American Association for the Study of Liver Diseases
Jun 28, 2011·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Rebecca S BahnUNKNOWN American Association of Clinical Endocrinologists
Jan 9, 2013·Nature Reviews. Endocrinology·Carol Wilson

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