Case Report: Delayed Diagnosis of Congenital Malaria by Plasmodium vivax in a Newborn of an Eritrean Woman with Varicella Infection

The American Journal of Tropical Medicine and Hygiene
Saba Gebremeskel TekleEmanuele Nicastri

Abstract

Congenital malaria (CM) is uncommon in both malaria-endemic and non-endemic countries. It may be caused by any Plasmodium spp., although Plasmodium falciparum and Plasmodium vivax are the more frequent etiologic agents. We report a case of delayed diagnosis of CM by P. vivax in a newborn of an Eritrean primigravida. The mother developed pregnancy-related immunodepression and varicella-zoster viral infection 9 days before natural delivery; therefore, the child was admitted in the neonatal intensive care unit (NICU) to administer specific varicella-zoster immunoglobulin prophylaxis and for clinical monitoring. During the NICU stay, the newborn presented a febrile syndrome with vomiting, anemia, and thrombocytopenia. A P. vivax severe malaria diagnosis was made by detecting trophozoites in the thick and thin blood smears. The infant was successfully treated with intravenous artesunate and clindamycin. Our experience suggests that malaria diagnostic tests need to be included in routine blood analyses in newborns with febrile syndrome from mothers with an epidemiologic link to malaria-endemic areas.

References

Jan 1, 1993·Annals of Tropical Paediatrics·J A AkindeleA E Abohweyere
Dec 1, 1995·Journal of Tropical Pediatrics·S E Ibhanesebhor
Jun 2, 2005·Journal of Tropical Pediatrics·M Y MukhtarA G Mafe
Oct 25, 2007·Tropical Medicine & International Health : TM & IH·Catherine FaladeMichael V Callahan
Jan 11, 2008·Journal of Perinatal Medicine·Oriol CollYves Ville
Mar 3, 2010·Malaria Journal·Veronica Del PuntaFrancesco Castelli
Mar 30, 2010·The American Journal of Tropical Medicine and Hygiene·Jeanne R PoespoprodjoNicholas M Anstey
Aug 19, 2011·Malaria Journal·Juan G Piñeros-JiménezSilvia Blair
Jun 13, 2015·Journal of Parasitic Diseases : Official Organ of the Indian Society for Parasitology·Preeti RaiJagdish Chandra
Sep 22, 2016·Case Reports in Pediatrics·Ravi BhatiaPriti Agrawal
Dec 16, 2016·The Turkish Journal of Pediatrics·Selvi Gülaşı, Nureddin Özdener
Jan 10, 2018·The American Journal of Tropical Medicine and Hygiene·Suryadi N N TaturaJoseph Tuda

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