Case report: hemosiderotic fibrohistiocytic lipomatous lesion: a clinicopathologic characterization.

Clinical Orthopaedics and Related Research
Vincent M MorettiChristian M Ogilvie

Abstract

A hemosiderotic fibrohistiocytic lipomatous lesion, also called hemosiderotic fibrolipomatous tumor, is a rare and recently described fibrolipomatous entity. Initially considered the result of a reactive inflammatory process from trauma or vascular disease, newer evidence suggests it may be neoplastic in origin. We report the case of a 56-year-old woman with a painful mass in the dorsal aspect of the foot diagnosed as a hemosiderotic fibrohistiocytic lipomatous lesion. We reviewed all 31 published cases of hemosiderotic fibrohistiocytic lipomatous lesions looking for common clinical, imaging, and histologic patterns. Hemosiderotic fibrohistiocytic lipomatous lesions occur predominantly in the fifth and sixth decades of life (average age, 49.5 years; range, 0.67-74 years). Females predominate 22 to 9. Thirteen of 28 patients had histories of trauma or vasculopathy. Twenty-six of 31 lesions were in the foot. The MRI signal of a hemosiderotic fibrohistiocytic lipomatous lesion follows fat in all sequences. Stranding or septations also frequently are seen. Histologically, the lesions are composed of three main elements in varying proportions: mature adipocytes, spindle cells, and hemosiderin pigment. Ten of 27 resected lesions recu...Continue Reading

References

Dec 6, 2000·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·C Marshall-Taylor, J C Fanburg-Smith
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Apr 15, 2008·Cancer Genetics and Cytogenetics·George R WettachAtiya Mansoor

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Citations

Jun 5, 2020·International Journal of Surgical Pathology·C Y PangWah Cheuk
Jun 5, 2012·Skeletal Radiology·Ty K SubhawongLaura M Fayad
Jul 14, 2017·Revista Brasileira De Ortopedia·Renata Margarida EtchebehereAntônio Sebastião Leitão

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