PMID: 9557075Apr 29, 1998Paper

Case report presentation for treatment of pure red cell aplasia

Polskie Archiwum Medycyny Wewnętrznej
J GiedrojćM Bielawiec

Abstract

We presented a case of a 34 year old male patient with pure red cell aplasia. He was treated with antithymocyte globulin (Pasteur Merieux, France) at a dose of 175 mg in 350 ml 0.9% NaCl in intravenous drip infusion--10 drip/min for 5 consecutive days. The therapy resulted in normalization of morphological parameters. Patient was under clinical observation. After 9 years when hemoglobin level decreased monoclonal antibody OKT3 og IgG 2a type (Cilag Ag International, Switzerland) at a dose of 5 mg intravenous for 10 consecutive days was applied. During the first and second therapy course symptoms of serum sickness and "flu like" syndrome was observed. The results of the two treatment appeared positive. We received normalization of morphological parameters.

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