Case reports of three atypical infiltrative keratitis events with high DK soft contact lens wear

Cornea
C SkotnitskyBrien A Holden

Abstract

We report three atypical infiltrative keratitis events in patients that had successfully worn highly oxygen permeable (Dk) soft contact lenses on an extended wear (EW) schedule for at least 15 months. These cases highlight the role of patient/practitioner education, patient compliance, examination, and appropriate referrals that are required to reduce the risk of complications during lens wear. Each patient had been wearing high Dk soft lenses on an EW schedule with monthly replacement for at least 15 months and presented with severe pain, redness, and photophobia. The events were characterized by focal infiltrate(s) with an overlying epithelial defect in the superior periphery to mid-periphery of the cornea and extensive diffuse infiltration. The signs and symptoms of each case were more severe than is typically associated with contact lens-related infiltrative keratitis. Because of the slow progression of signs and relatively fast resolution, the cases were not found to be microbial keratitis. Although high Dk soft contact lenses overcome hypoxia-associated complications associated with extended wear, patients and practitioners must be vigilant as adverse events can still occur and in rare instances can be severe. Education a...Continue Reading

References

Jul 1, 1986·Survey of Ophthalmology·J B RobinH E Kaufman
Mar 1, 1993·Optometry and Vision Science : Official Publication of the American Academy of Optometry·R L TerryA Back
Sep 1, 1997·Current Eye Research·E B PapasB A Holden
Jan 10, 1998·Optometry and Vision Science : Official Publication of the American Academy of Optometry·M D WillcoxD F Sweeney
Feb 14, 1998·Optometry and Vision Science : Official Publication of the American Academy of Optometry·L AlvordL Winterton
Mar 14, 2000·Experimental Eye Research·A Thakur, M D Willcox
Jan 4, 2001·Optometry and Vision Science : Official Publication of the American Academy of Optometry·L KeayB A Holden
Feb 13, 2001·The British Journal of Ophthalmology·F StapletonL Keay
Mar 27, 2001·Optometry and Vision Science : Official Publication of the American Academy of Optometry·M CoveyB A Holden

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Citations

Nov 24, 2005·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Meng C LinKenneth A Polse
Nov 24, 2005·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Fiona StapletonJoseph Shovlin
Jun 25, 2005·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Kate E Weidemann, Carol Lakkis
Apr 17, 2007·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Fiona StapletonNerida Cole
Mar 13, 2013·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Percy Lazon de la JaraBrien A Holden
Jul 16, 2003·Eye & Contact Lens·Marc W RobboyCarolyn M Kalsow
Jan 18, 2006·Eye & Contact Lens·E A SzliterLinda D Hazlett

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