"Caseness" for depression and anxiety in a depressed outpatient population: symptomatic outcome as a function of baseline diagnostic categories.

Primary Care Companion to the Journal of Clinical Psychiatry
Koen DemyttenaereM Bauer

Abstract

To examine the diagnostic status of patients enrolled in the Factors Influencing Depression Endpoints Research (FINDER) study and symptomatic outcomes and baseline characteristics associated with remission 6 months after commencing antidepressant therapy. Status of clinically diagnosed depressed patients was based on self-rated Hospital Anxiety and Depression Scale (HADS) scores. Five diagnostic categories were defined: noncaseness, mixed anxiety-depression (subthreshold depressive and anxious symptomatology), caseness for depression, caseness for anxiety, and caseness for comorbid anxiety-depression. Assessments included the Somatic Symptom Inventory and health-related quality of life (HRQoL) using the Medical Outcomes Study 36-item Short-Form Health Survey. Remission rates (based on HADS noncaseness for both depression and anxiety) and their associations with baseline characteristics were investigated. Patients were enrolled between May 2004 and September 2005. Of the 3,353 patients enrolled, 66.4% met the HADS criteria for probable depressive disorder and 74.1% met the HADS criteria for probable anxiety disorder. Somatic symptom severity (painful and nonpainful) was highest and HRQoL was lowest in the comorbid anxiety-depres...Continue Reading

Citations

Aug 13, 2011·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Koen Demyttenaere
Dec 30, 2014·Journal of Affective Disorders·Koen DemyttenaereKees van Heeringen
Dec 30, 2014·Journal of Affective Disorders·Koen DemyttenaereKees van Heeringen
Oct 8, 2016·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Koen Demyttenaere
Jan 1, 2020·Molecular Genetics & Genomic Medicine·Ivo Emilio da Cruz JungMarta Maria Medeiros Frescura Duarte
May 20, 2020·CNS Spectrums·Koen DemyttenaereMassimo Di Giannantonio
May 22, 2020·International Review of Psychiatry·Koen Demyttenaere, Elke Heirman
Jul 3, 2018·The International Journal of Neuropsychopharmacology·Koen Demyttenaere, Zeno Van Duppen
Jul 21, 2021·The Australian and New Zealand Journal of Psychiatry·Bénédicte NobilePhilippe Courtet

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