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CasFinder: Flexible algorithm for identifying specific Cas9 targets in genomes

bioRxiv

May 12, 2014

John AachGeorge M Church

Abstract

CRISPR/Cas9 systems enable many molecular activities to be efficiently directed in vivo to user-specifiable DNA sequences of interest, including generation of dsDNA cuts and nicks, transcriptional activation and repression, and fluorescence. CRISPR targeting relies on base pairing of sh...read more

Mentioned in this Paper

Site
DNA Binding Domain
In Vivo
Transcript
MMP3 protein, human
Laboratory mice
Neisseria meningitidis
Plasmids
Streptococcus thermophilus
Widening
27
86
Paper Details
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CasFinder: Flexible algorithm for identifying specific Cas9 targets in genomes

bioRxiv

May 12, 2014

John AachGeorge M Church

PMID: 990005074

DOI: 10.1101/005074

Abstract

CRISPR/Cas9 systems enable many molecular activities to be efficiently directed in vivo to user-specifiable DNA sequences of interest, including generation of dsDNA cuts and nicks, transcriptional activation and repression, and fluorescence. CRISPR targeting relies on base pairing of sh...read more

Mentioned in this Paper

Site
DNA Binding Domain
In Vivo
Transcript
MMP3 protein, human
Laboratory mice
Neisseria meningitidis
Plasmids
Streptococcus thermophilus
Widening
27
86

Similar Papers Found In These Feeds

Paper Details
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