PMID: 9175388Mar 1, 1997Paper

Castleman's disease: a clinicopathologic study of 12 cases

Journal of the Medical Association of Thailand = Chotmaihet Thangphaet
V KasantikulV Panichabhongse

Abstract

Castleman's disease observed in 12 Thai patients was investigated. The male to female ratio was 1:3. Peak prevalence was in the third and fourth decades. It is suggested that the disease in Orientals tends to have extrathoracic mass more often than in Caucasians. Solitary non-tender slow growing mass was the most common symptom. Generalized lymphadenopathy in association with cutaneous plasmocytoma was noted in one example while asymptmatic pelvic lesion in a patient was discovered incidentally. Histologically, the hyaline-vascular type was found in 8 instances, the remainders were plasma-cell type. Surgery was effective for localized lesions while systemic form could benefit from chemotherapy.

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Castleman Disease

Castleman disease is a rare disorder that involves an overgrowth of cells in the lymph nodes. Unicentric Castleman disease affects one lymph node, usually in the chest or abdomen. Multicentric Castleman disease affects multiple lymph nodes, commonly located in the neck, collarbone, underarm and groin areas. Discover the latest research on Castleman disease here.

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