PMID: 15224829Jul 1, 2004Paper

Castleman's disease as an unusual neck mass: case report

The Annals of Otology, Rhinology, and Laryngology
Mehmet Akif SomdasErcihan Guney

Abstract

Castleman's disease is a rare, benign disease of unknown cause that induces reactive lymph node hyperplasia, most commonly in the mediastinum. It has 2 histologic subtypes: hyaline vascular and plasma cellular. A definitive diagnosis necessitates tissue biopsy. A specimen may be even misdiagnosed as lymphoma in frozen section. Surgery is the treatment of choice for the solitary form, whereas chemotherapy, radiotherapy, and steroids are proposed for the multicentric type. A neck mass diagnosed as Castleman's disease in a 48-year-old woman is reported.

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Citations

Jan 14, 2005·Mund-, Kiefer- und Gesichtschirurgie : MKG·F HölzleK-D Wolff
Jan 16, 2008·Journal of the Chinese Medical Association : JCMA·Chih-Cheng ChenChing-Ping Wang
Aug 15, 2014·The Journal of Craniofacial Surgery·Yasin Kursad VarsakAhmet Bedri Ozer

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Castleman Disease

Castleman disease is a rare disorder that involves an overgrowth of cells in the lymph nodes. Unicentric Castleman disease affects one lymph node, usually in the chest or abdomen. Multicentric Castleman disease affects multiple lymph nodes, commonly located in the neck, collarbone, underarm and groin areas. Discover the latest research on Castleman disease here.

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