Castor oil as secondary carbon source for production of sophorolipids using Starmerella bombicola NRRL Y-17069

Journal of Oleo Science
Vinit Bajaj, Uday Annapure

Abstract

Sophorolipids (SLs), a prominent member of the biosurfactants family are produced in acidic and/or lactonic form by yeast Starmerella bombicola NRRL Y-17069 when grown on hydrophilic or hydrophobic or both carbon sources. In current study, ricinoleic acid rich castor oil (10%) was used as hydrophobic and glycerol (10%) was used as hydrophilic carbon source. The yields of 24.5 ± 0.25 g/l sophorolipids were analyzed by anthrone and HPLC method which further increased upto 40.24 ± 0.76 g/l sophorolipids using fed batch process at 5L fermenter level. The structures of sophorolipids synthesized on castor oil were elucidated by liquid chromatography-mass spectrometer (LC-MS), (13)C and (1)H NMR. The results indicated that the ricinoleic acid (RA) gets hydroxylated at ω-1 position but incorporated into sophorolipids through already available hydroxyl group at 12(th) position. It resulted in the production of a novel sophorolipids with hydroxyl fatty acid as side chain and has applications as surfactant for novel drug delivery, anti microbial agent, cosmetic ingredient and emulsifier.

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Citations

Aug 25, 2015·FEMS Yeast Research·Karen M J SaerensWim Soetaert
Sep 21, 2017·Applied Microbiology and Biotechnology·Silke Claus, Inge N A Van Bogaert
Nov 30, 2019·Applied Microbiology and Biotechnology·Xiaojing MaRisheng Yao
Dec 19, 2020·Comprehensive Reviews in Food Science and Food Safety·Ilyes DammakCarlos Adam Conte-Junior
Jun 17, 2021·Bioprocess and Biosystems Engineering·André Felipe da SilvaDiogo Robl
Jul 30, 2021·Journal of Industrial Microbiology & Biotechnology·Alexander BeckSusanne Zibek

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