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Catalpol and Mannitol, Two Components of Rehmannia glutinosa , Exhibit Anticonvulsant Effects Probably via GABAA Receptor Regulation

Biomolecules & Therapeutics

Nov 18, 2019

Mikyung KimHee Jin Kim

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Abstract

Epilepsy is a brain disorder that affects millions of people worldwide and is usually managed using currently available antiepileptic drugs, which result in adverse effects and are ineffective in approximately 20-25% of patients. Thus, there is growing interest in the development of new...read more

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Anticonvulsants
Antiepileptic Agents
Brain Diseases
Electroencephalography
Epilepsy
Laboratory Procedures
Mannitol
Laboratory mice
Persons
Pentylenetetrazole
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Catalpol and Mannitol, Two Components of Rehmannia glutinosa , Exhibit Anticonvulsant Effects Probably via GABAA Receptor Regulation

Biomolecules & Therapeutics

Nov 18, 2019

Mikyung KimHee Jin Kim

PMID: 31739380

DOI: 10.4062/biomolther.2019.130

Abstract

Epilepsy is a brain disorder that affects millions of people worldwide and is usually managed using currently available antiepileptic drugs, which result in adverse effects and are ineffective in approximately 20-25% of patients. Thus, there is growing interest in the development of new...read more

Mentioned in this Paper

Anticonvulsants
Antiepileptic Agents
Brain Diseases
Electroencephalography
Epilepsy

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