Catalysis by the RNA subunit of RNase P--a minireview.

Gene
Sidney AltmanK Peck

Abstract

RNase P, an enzyme that contains both RNA and protein components, cleaves tRNA precursors to generate mature 5' termini. The catalytic activity of RNase P resides in the RNA component, with the protein cofactor affecting the rate of the cleavage reaction. The reaction is also influenced by the nature of the tRNA substrate.

References

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Aug 5, 1988·Journal of Molecular Biology·N Lumelsky, S Altman

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