Catalytic amplification based on hole-transporting materials as efficient metal-free electrocatalysts for non-enzymatic glucose sensing

Analytica Chimica Acta
Yue GuMing Yang

Abstract

Hole-transporting materials with tunable structures and properties are mainly applied in organic light-emitting diodes as transport layer. But their catalytic properties as signal amplifiers in biological assays are seldom reported. In this paper, a starburst molecule, 4,4,4″-tri(N-carbazolyl)-triphenylamine (TCT), containing a triphenylamine as the central core and three carbazoles as the peripheral functional groups was designed and synthesized. Subsequently, the hole-transporting material based on the TCT polymer, poly(TCT) (PTCT), was achieved via a low-cost electrochemical method and exploited as an efficient metal-free electrocatalyst for non-enzymatic glucose detection. Here, this hole-transporting material served three purposes: electrochemical recognition (owing to hydrogen bonding interaction and the biomimetic microenvironment created by the polymer), electrocatalysis (owing to the hole-transporting capability of triphenylamine and the catalytic property of carbazole), and signal amplification (owing to energy migration along the conductive polymer backbone). The electrocatalytic and sensing performances of the sensor based on PTCT were evaluated in detail. Results revealed that the PTCT film could efficiently cataly...Continue Reading

References

May 8, 2001·Biosensors & Bioelectronics·Z ChengX Yang
Sep 11, 2003·Analytical Chemistry·Sejin ParkHee Chan Kim
Jan 24, 2006·Chemistry : a European Journal·Bikash Kumar Jena, C Retna Raj
Aug 29, 2007·Analytica Chimica Acta·Sejin ParkTaek Dong Chung
Jul 16, 2008·Biosensors & Bioelectronics·Yu BaiChangqing Sun
Dec 14, 2011·Biosensors & Bioelectronics·Yuchan ZhangYu Lei
May 25, 2012·Chemical Communications : Chem Comm·Xuewan WangPeng Chen

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