Catalytic defluorinative [3 + 2] cycloaddition of trifluoromethylalkenes with alkynes via reduction of nickel(II) fluoride species

Dalton Transactions : an International Journal of Inorganic Chemistry
Takeshi FujitaJunji Ichikawa

Abstract

Nickel-catalyzed [3 + 2] cycloaddition of 2-trifluoromethyl-1-alkenes with alkynes via domino C-F bond activation was achieved by sequential β-fluorine elimination. The nickel(ii) fluoride species formed in this reaction was reduced by a diboron compound, regenerating the catalytically active nickel(0) species.

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Citations

May 11, 2017·Journal of the American Chemical Society·Andrés García-DomínguezCristina Nevado
Nov 2, 2016·Dalton Transactions : an International Journal of Inorganic Chemistry·Theresia AhrensReik Laubenstein
Aug 21, 2018·Chemical Communications : Chem Comm·Jean-Denys Hamel, Jean-François Paquin
Jun 29, 2018·Angewandte Chemie·Takeshi FujitaJunji Ichikawa
Oct 12, 2018·Angewandte Chemie·Young Jin JangMark Lautens
Mar 28, 2019·Chemistry : a European Journal·Angelo Frei
Oct 30, 2019·Chemical Communications : Chem Comm·Feitao TianJian Yu
Jun 12, 2019·Journal of the American Chemical Society·Stephen R SardiniM Kevin Brown
Aug 21, 2018·Journal of the American Chemical Society·Pin GaoM Kevin Brown

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