Catalytic dehydrogenative dual functionalization of ethers: dealkylation-oxidation-bromination accompanied by C-O bond cleavage via aerobic oxidation of bromide

Chemical Communications : Chem Comm
Katsuhiko MoriyamaHideo Togo

Abstract

Catalytic dehydrogenative dual functionalization (DDF) of ethers via oxidation, dealkylation, and α-bromination by the aerobic oxidation of bromide was developed to obtain the corresponding α-bromo ketones in high yields. In particular, the reaction of substituted tetrahydrofurans as cyclic ethers provided 3,3-dibromo tetrahydrofuran-2-ols in high yields selectively through the double α-bromination.

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Aug 10, 2011·The Journal of Organic Chemistry·Katsuhiko MoriyamaHideo Togo
Jul 19, 2012·Chemical Communications : Chem Comm·Katsuhiko MoriyamaHideo Togo
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Citations

Nov 16, 2017·Chemical Communications : Chem Comm·Redouane BeniazzaJean-Marc Vincent

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