Catamenial diabetic ketoacidosis and catamenial hyperglycemia: case report and review of the literature

The American Journal of the Medical Sciences
Fernando OvalleBarbara Gower

Abstract

Diabetic ketoacidosis (DKA), an acute and potentially life-threatening complication of diabetes mellitus, is frequently the result of a precipitating illness or nonadherence to treatment; however, despite a thorough history, physical, radiologic, and laboratory examination, a specific cause or precipitating event cannot be identified in a significant number of cases. To report 2 cases of recurrent DKA, and hyperglycemic crisis, associated to the menstrual cycle, and provide a review of the medical literature. The clinic and hospital medical records of 2 subjects with type 1 diabetes mellitus (T1DM) and unexplained DKA are reviewed. An electronic MEDLINE search of relevant medical literature published from 1965 to 2007 was performed; additionally, the reference lists of the identified articles and other sources, such as textbook chapters and meeting abstracts, were reviewed for related publications. To date there have been 7 reported cases in the literature demonstrating an association between menstruation and DKA. The 2 new cases presented here highlight the potentially significant changes in glucose metabolism that may occasionally be observed during the late luteal and decidual phases of the menstrual cycle; moreover, these c...Continue Reading

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Citations

Dec 14, 2011·Autoimmunity Reviews·Sabine Oertelt-Prigione
Aug 12, 2014·Current Opinion in Obstetrics & Gynecology·Anna Lea Altshuler, Paula J Adams Hillard

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