Catastrophic antiphospholipid syndrome related to severe ovarian hyperstimulation

Clinical Rheumatology
V GinerJ Redón

Abstract

Antiphospholipid syndrome (APS) is a cause of infertility and fetal loss. Ovarian stimulation can induce previously unknown APS. Ovarian hyperstimulation syndrome (OHS) is uncommon but potentially life-threatening, as well as catastrophic APS. A woman that simultaneously developed a severe OHS and a catastrophic APS is described in this paper. Both entities produced thrombotic cardiac and brain thrombosis. A peculiar mechanism of cardiac ischemia is also described. In spite of the life-threatening risk of this situation, the indication for preventive anti-aggregation and/or anticoagulation is not clear.

References

Oct 1, 1996·Human Reproduction·J BalaschJ A Vanrell
Nov 5, 1999·Human Reproduction·A P Murdoch, I Evbuomwan
Dec 28, 1999·Human Reproduction·P E Egbase
Apr 20, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology·D VinatierJ L Houpeau
Aug 13, 2002·Journal of Korean Medical Science·Eun-Jung KooChoong-Kun Ha
Dec 25, 2002·Human Reproduction Update·Annick Delvigne, Serge Rozenberg
Sep 23, 2003·Gynécologie, obstétrique & fertilité·O Meyer

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Citations

Feb 1, 2007·Journal of Thrombosis and Thrombolysis·Antonio GirolamiBruno Girolami
Mar 8, 2014·Revue neurologique·V KumakoN Nighoghossian
Aug 15, 2008·Human Reproduction Update·Scott M Nelson, Ian A Greer
May 24, 2011·Fertility and Sterility·Zhao Jing, Li Yanping
May 16, 2009·Thrombosis Research·Scott M Nelson
Jul 12, 2016·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Pawani Sachar, Kumar Rajamani
Mar 12, 2009·Current Opinion in Obstetrics & Gynecology·Wee Shian Chan
Apr 30, 2020·American Journal of Reproductive Immunology : AJRI·Asmaa BeltagyCecilia B Chighizola
Jun 27, 2019·Expert Opinion on Drug Safety·V S VanniP Rovere-Querini
Aug 21, 2019·International Journal of Clinical Endocrinology and Metabolism·Mohammed Al-SadawiSamy I McFarlane

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