Catching the imposter in the brain: The case of Capgras delusion.

Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Arturo NuaraDoriana De Marco

Abstract

Here we describe a rare case of Capgras delusion - a misidentification syndrome characterized by the belief that a person has been replaced by an imposter - in a patient without evident neurological or psychiatric symptoms. Intriguingly, delusional belief was selective for both person and modality, as the patient believed that his son - not his daughter or other relatives - was substituted with an imposter only while being in presence of him and looking at his face, but not when merely listening to his voice. A neuroanatomical reconstruction obtained integrating morphological and functional patient's neuroimaging data highlighted two main peculiarities: a compression of the rostral portion of right temporal lobe due to a large arachnoid cyst, and a bilaterally reduced metabolism of frontal areas. Autonomic data obtained from thermal infra-red camera and skin conductance recordings showed that a higher sympathetic activation was evoked by the observation of daughter's face, relative to the observation of the son's face as well as of not-familiar faces; conversely, daughter and son voices elicited a similar sympathetic activation, higher relative to not-familiar voices, indicating a modality-dependent dissociation consistent with...Continue Reading

References

Aug 1, 1976·Archives of General Psychiatry·E L Merrin, P M Silberfarb
Sep 1, 1992·Journal of the American Geriatrics Society·T N Tombaugh, N J McIntyre
Jan 1, 1991·Neuroradiology·T BeckerM Nadjmi
Aug 1, 1990·The British Journal of Psychiatry : the Journal of Mental Science·H D Ellis, A W Young
Aug 1, 1989·Journal of the American Geriatrics Society·T SunderlandJ H Grafman
Oct 1, 1981·The British Journal of Psychiatry : the Journal of Mental Science·J ToddG Wallis
Jan 1, 1994·Psychopathology·H D EllisN Retterstøl
Jan 1, 1994·Psychopathology·A W YoungT K Szulecka
May 1, 1993·The British Journal of Psychiatry : the Journal of Mental Science·A W YoungD J Hellawell
Sep 1, 1993·The British Journal of Clinical Psychology·S WrightD J Hellawell
Apr 12, 1996·Biological Psychology·P H Venables, D A Mitchell
Jul 22, 1997·Proceedings. Biological Sciences·H D EllisK W De Pauw
Feb 5, 2000·Nature·P BelinB Pike
May 29, 2000·Trends in Cognitive Sciences·J V HaxbyM I Gobbini
Apr 5, 2001·Trends in Cognitive Sciences·H D. Ellis, M B. Lewis
Dec 6, 2005·Consciousness and Cognition·Todd E Feinberg, Julian Paul Keenan
Apr 8, 2006·Trends in Cognitive Sciences·Vaughan BellHadyn D Ellis
Sep 20, 2006·Experimental Aging Research·Annapaola PrestiaGiovanni B Frisoni
Nov 10, 2006·Journal of Neurophysiology·K M GothardD G Amaral
Apr 25, 2007·Cognitive Neuropsychiatry·Gianni BrighettiCristina Ottaviani
Jul 27, 2007·The Quarterly Journal of Experimental Psychology : QJEP·Max Coltheart
Dec 12, 2007·Archives of Neurology·Keith A Josephs
Aug 30, 2008·Human Brain Mapping·Margot J TaylorEmmanuel J Barbeau
Apr 16, 2010·Annals of the New York Academy of Sciences·Max Coltheart
Feb 1, 2000·Cognitive Neuropsychology·N BreenM Coltheart
Sep 9, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Helen BlankKatharina von Kriegstein
Oct 8, 2011·NeuroImage·Mark JenkinsonStephen M Smith
Jan 18, 2012·NeuroImage·Bruce Fischl
Jul 10, 2012·Magnetic Resonance Imaging·Andriy FedorovRon Kikinis
Oct 1, 1995·Journal of Cognitive Neuroscience·D TranelA R Damasio
Aug 30, 2013·Journal of Cognitive Neuroscience·Peter Mende-SiedleckiAlexander Todorov
Apr 5, 2015·Trends in Cognitive Sciences·Kevin S Weiner, Kalanit Grill-Spector
Aug 13, 2015·Brain : a Journal of Neurology·Aaron D BoesMichael D Fox
Aug 19, 2015·Proceedings of the National Academy of Sciences of the United States of America·Meike RamonBruno Rossion
Oct 20, 2015·Nature Neuroscience·Florian MormannRalph Adolphs
Jan 17, 2016·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Jason J S Barton, Sherryse L Corrow
Feb 24, 2016·The Journal of Neuropsychiatry and Clinical Neurosciences·Ryan Darby, Sashank Prasad
Jan 14, 2017·Brain : a Journal of Neurology·R Ryan DarbyMichael D Fox
Dec 12, 2017·Brain : a Journal of Neurology·Claudia RoswandowitzKatharina von Kriegstein
Feb 12, 2019·Communications Biology·Artem PlatonovGuy A Orban

❮ Previous
Next ❯

Citations

Oct 29, 2021·Frontiers in Psychiatry·Sélim Benjamin GuessoumMarie Rose Moro
Dec 11, 2021·Cognitive Neuropsychiatry·Max Coltheart, Martin Davies

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
G Denes
Southern Medical Journal
E L Sandidge
Proceedings. Biological Sciences
H D. EllisK W de Pauw
Annals of General Psychiatry
Sulochana JoshiRabi Shakya
© 2022 Meta ULC. All rights reserved