Catecholamine innervation of the piriform cortex: a tracing and immunohistochemical study in the rat

Brain Research
F Datiche, M Cattarelli

Abstract

In order to determine the origin of the catecholamine innervation of the rat piriform cortex (PC), we combined retrograde transport of the B subunit of the cholera toxin (CTb) with tyrosine hydroxylase (TH) immunohistochemistry. A substantial number of CTb retrogradely labeled cells was found in the parabrachial pigmented, paranigral and interfascicular nuclei of the ventral tegmental area and the dorsal part of the locus coeruleus, whereas nearly no labeling was noted in the substantia nigra. Following TH immunohistochemistry on the same sections, most if not all of the CTb labeled cells were also TH immunoreactive. Occasional double-labeled cells were also observed in the anterior part of the raphe dorsal nucleus. As visualized with dopamine beta-hydroxylase, dopamine or TH immunohistochemistry, the noradrenaline fibers were homogeneously distributed whereas the dopamine fibers showed rostro-caudal and latero-medial differences. The distribution of TH fibers overlapped both patterns. Our report suggests that the heterogeneous distribution of the DA fibers could support a differential centrifugal modulation of the olfactory information processing throughout the PC.

References

Mar 12, 1990·Brain Research·T R Stratford, D Wirtshafter
Oct 1, 1986·Physiology & Behavior·J P Kroon, A L Riley
Mar 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·T C RainbowB B Wolfe
Jan 1, 1994·Brain Research Bulletin·R M Sullivan, D A Wilson

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Citations

Apr 29, 1999·Journal of Neuroscience Research·C WangK M Johnson
Jun 28, 2011·Journal of Molecular Neuroscience : MN·Xin HengWeidong Le
Mar 18, 1999·Pharmacology, Biochemistry, and Behavior·S M AjaD W Gietzen
Aug 1, 1997·Progress in Neurobiology·P LitaudonM Cattarelli
Oct 29, 2010·Learning & Memory·Max L Fletcher, Wei R Chen
Sep 19, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Mary F Kritzer, Lela M Creutz
Dec 24, 2011·Neurobiology of Disease·Richard L Doty
Oct 1, 2016·Perception·Emmanuelle Courtiol, Donald A Wilson
Feb 9, 2006·Neuroscience and Behavioral Physiology·T BolkvadzeA Sh Tsitsishvili
Oct 31, 2020·Frontiers in Neuroscience·Simona CovielloJuan Nacher
Apr 7, 2021·Integrative and Comparative Biology·Matheus Macedo-Lima, Luke Remage-Healey

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