Catecholamine plasma levels, IFN-γ serum levels and antibodies production induced by rabies vaccine in dogs selected for their paw preference

Laterality
M SiniscalchiA Quaranta

Abstract

To explore the possible role of the sympathetic nervous activity in the asymmetrical crosstalk between the brain and immune system, catecholamine (E, NE) plasma levels, Interferon-γ (IFN-γ) serum levels and production of antibodies induced by rabies vaccine in dogs selected for their paw preference were measured. The results showed that the direction of behavioural lateralization influenced both epinephrine levels and immune response in dogs. A different kinetic of epinephrine levels after immunization was observed in left-pawed dogs compared to both right-pawed and ambidextrous dogs. The titers of antirabies antibodies were lower in left-pawed dogs than in right-pawed and ambidextrous dogs. Similarly, the IFN-γ serum levels were lower in left-pawed dogs than in the other two groups. Taken together, these findings showed that the left-pawed group appeared to be consistently the different group stressing the fundamental role played by the sympathetic nervous system as a mechanistic basis for the crosstalk between the brain and the immune system.

References

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Jul 5, 2002·Brain, Behavior, and Immunity·J Martin MartinsJ Charneco da Costa
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Jul 22, 2004·Behavioural Brain Research·A QuarantaG Vallortigara
Mar 21, 2007·Current Biology : CB·A QuarantaG Vallortigara
Oct 10, 2008·PloS One·Marcello SiniscalchiLesley J Rogers
Jan 12, 2010·Behavioural Brain Research·Marcello SiniscalchiAngelo Quaranta
Aug 23, 2011·Brain, Behavior, and Immunity·Virginia M Sanders
May 1, 2012·Animal Cognition·Marcello SiniscalchiAngelo Quaranta
Jun 21, 2012·Laterality·Marcello SiniscalchiAngelo Quaranta

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Citations

Aug 23, 2016·Viruses·Terence P Scott, Louis H Nel
Aug 16, 2017·Veterinary Pathology·Kristen R RichterAngela M Mexas

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Software Mentioned

statistical package for social science ( SPSS )

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