PMID: 1199813Nov 1, 1975Paper

Catecholamines in plasma and urine in patients with essential hypertension determined by double-isotope derivative techniques

Acta Medica Scandinavica
E B Pedersen, N J Christensen

Abstract

Employing double-isotope derivative techniques, noradrenaline and adrenaline have been determined in plasma and in urine and dopamine in urine in 21 patients with essential hypertension as well as in 32 controls. Plasma noradrenaline rose with age in both groups of subjects. No differences were observed in plasma noradrenaline and plasma adrenaline in the resting supine position and in urinary excretion of noradrenaline and dopamine in hypertensive patients as compared to control subjects. Urinary excretion of adrenaline was somewhat lower in the hypertensives than in the controls. Treatment with alprenolol, a beta-adrenergic blocking agent, did not influence noradrenaline and adrenaline in plasma in the basal state or the urinary excretion of the three catecholamines. The combined treatment with alprenolol and hydralazine was followed by a significant rise in plasma noradrenaline. It is concluded that the adrenergic activity evaluated by circulating catecholamines is normal in most patients with essential hypertension.

References

May 1, 1973·Scandinavian Journal of Clinical and Laboratory Investigation·N J Christensen
Sep 1, 1973·The American Journal of Medicine·V DeQuattro, Y Miura
Aug 1, 1973·Clinical Science and Molecular Medicine·N J Christensen
Oct 1, 1972·Scandinavian Journal of Clinical and Laboratory Investigation·M S Christensen, N J Christensen
Mar 22, 1973·The New England Journal of Medicine·W J LouisS Anavekar
Oct 1, 1968·The Journal of Clinical Investigation·V DeQuattro, A Sjoerdsma
Apr 1, 1964·The American Journal of Cardiology·P A SERRANOA RAMIREZDELANGEL
Jul 16, 1964·The New England Journal of Medicine·S BRUNJES

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Citations

Dec 1, 1978·European Journal of Clinical Pharmacology·N J ChristensenP E Nielsen
Apr 1, 1988·Scandinavian Journal of Clinical and Laboratory Investigation·S R Johansson, A Hjalmarson
Jan 1, 1983·Experimental Aging Research·N R Cutler, J E Hodes
Jan 1, 1983·Acta Medica Scandinavica. Supplementum·N J Christensen
Aug 25, 2010·Hypertension·Niels Juel Christensen
Oct 15, 1981·Klinische Wochenschrift·H HörtnaglF Wewalka
Jan 1, 1982·British Journal of Clinical Pharmacology·P Dominiak, H Grobecker
Jan 1, 1980·Clinical and Experimental Hypertension : CHE·I J KopinI Yamaguchi
Aug 1, 1984·Journal of the American Geriatrics Society·V Fiorica
Dec 1, 1985·Clinical Physiology·C SachsL Kaijser
Apr 1, 1982·European Journal of Clinical Investigation·P C RubinJ L Reid
May 1, 1982·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·A D Merkel, A Barbeau
Dec 1, 1979·Irish Journal of Medical Science·G A FitzGerald
Jul 7, 1977·The New England Journal of Medicine
Jan 1, 1976·Acta Medica Scandinavica. Supplementum·N J Christensen
Jan 1, 1979·Acta Medica Scandinavica. Supplementum·N J Christensen
Feb 1, 1979·Archives internationales de physiologie et de biochimie·J JuchmèsA Brose
May 1, 1980·Intensive Care Medicine·H HörtnaglH Hörtnagl
Jan 2, 1981·Klinische Wochenschrift·M LehmannG Simon
Jan 1, 1988·International Urology and Nephrology·J Solski, A Ksiazek
Jan 1, 1981·Acta Physiologica Scandinavica·B G WallinL E Lindblad
Oct 1, 1980·Journal of the American Geriatrics Society·T MandaiY Kumahara

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