Catecholase activity of a series of dicopper(II) complexes with variable Cu-OH(phenol) moieties

Inorganic Chemistry
Ademir NevesSergei Ostrovsky

Abstract

The catecholase activity of a series of dicopper(II) complexes containing different numbers of phenol groups coordinated to the metal centers was studied to identify functional as well as structural models for the type III copper enzymes tyrosinase and catechol oxidase. The syntheses and characterization of complexes [Cu(2)(H(2)bbppnol)(mu-OAc)(H(2)O)(2)]Cl(2).2H(2)O (1) and [Cu(2)(Hbtppnol)(mu-OAc)](ClO(4))(2) (2) were previously reported by us (Inorg. Chim. Acta 1998, 281, 111-115; Inorg. Chem. Commun. 1999, 2, 334-337), and complex [Cu(2)(P1-O(-))(OAc(-))](ClO(4))(2) (3) was previously reported by Karlin et al. (J. Am. Chem. Soc. 1997, 119, 2156-2162). The catalytic activity of the complexes 1-3 on the oxidation of 3,5-di-tert-butylcatechol was determined spectrophotometrically by monitoring the increase of the 3,5-di-tert-butyl-o-benzoquinone characteristic absorption band at about 400 nm over time in methanol saturated with O(2)/aqueous buffer pH 8 solutions at 25 degrees C. The complexes were able to oxidize 3,5-di-tert-butylcatechol to the corresponding o-quinone with distinct catalytic activity. A kinetic treatment of the data based on the Michaelis-Mentèn approach was applied. The [Cu(2)(H(2)bbppnol)(mu-OAc)(H(2)O)(2)]...Continue Reading

Citations

Jun 22, 2013·Chemical Reviews·Scott E AllenMarisa C Kozlowski
Aug 23, 2012·Inorganic Chemistry·Peter CombaJohannes Straub
Aug 29, 2006·Chemical Society Reviews·Iryna A KovalJan Reedijk
Jun 12, 2014·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Ria SanyalDebasis Das
Jan 12, 2008·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Sarah J SmithMark J Riley
Jun 24, 2016·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Franziska WendtFelix Tuczek
Jan 23, 2015·Dalton Transactions : an International Journal of Inorganic Chemistry·Alokesh HazariAshutosh Ghosh
Mar 23, 2017·Dalton Transactions : an International Journal of Inorganic Chemistry·Deepak Bansal, Rajeev Gupta
Feb 9, 2017·Dalton Transactions : an International Journal of Inorganic Chemistry·Yogendra Pratap SinghR J Butcher
Dec 3, 2015·Dalton Transactions : an International Journal of Inorganic Chemistry·Prateeti ChakrabortyDebasis Das
Mar 17, 2016·Dalton Transactions : an International Journal of Inorganic Chemistry·Krishna ChattopadhyayDebashis Ray
Aug 12, 2016·Dalton Transactions : an International Journal of Inorganic Chemistry·Tufan Singha MahapatraDebashis Ray
Oct 11, 2016·Dalton Transactions : an International Journal of Inorganic Chemistry·José A F de OliveiraAdailton J Bortoluzzi
Nov 10, 2011·Chemistry : a European Journal·Kun ZhangLaurent Bonneviot
Oct 23, 2018·Dalton Transactions : an International Journal of Inorganic Chemistry·Adriana M MagherusanAidan R McDonald
Nov 27, 2018·Dalton Transactions : an International Journal of Inorganic Chemistry·Manisha DasDebashis Ray
Jan 5, 2019·Dalton Transactions : an International Journal of Inorganic Chemistry·Manisha DasDebashis Ray
Jul 13, 2006·Chemistry : a European Journal·Iryna A KovalJan Reedijk
Mar 29, 2008·Dalton Transactions : an International Journal of Inorganic Chemistry·Edgar MijangosLaura Gasque
Oct 20, 2005·Dalton Transactions : an International Journal of Inorganic Chemistry·Vera S I SprakelRoeland J M Nolte
Jun 15, 2007·Dalton Transactions : an International Journal of Inorganic Chemistry·Jacky ChenLev N Zakharov
Oct 25, 2013·Dalton Transactions : an International Journal of Inorganic Chemistry·Totan GhoshDebasis Das
Dec 24, 2004·Dalton Transactions : an International Journal of Inorganic Chemistry·Tatiana M SimándiLászló I Simándi
Aug 8, 2020·Dalton Transactions : an International Journal of Inorganic Chemistry·Sabarni DuttaAshutosh Ghosh
Nov 13, 2004·Dalton Transactions : an International Journal of Inorganic Chemistry·Soumen MukherjeePhalguni Chaudhuri
May 6, 2020·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Aarón TeránÁngel Gutiérrez
Sep 10, 2004·Dalton Transactions : an International Journal of Inorganic Chemistry·Chang-Tong YangJagadese J Vittal
Jan 8, 2021·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Mariappan MuraliBalasubramaniam Selvakumaran

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.