Categorical perception of somesthetic stimuli: psychophysical measurements correlated with neuronal events in primate medial premotor cortex

Cerebral Cortex
R RomoA Hernández

Abstract

In this paper we describe a type of neuron of the medial premotor cortex (MPC) that discharged differentially during a categorization task and reflected in their activity whether the speed of a tactile stimulus was low or high. The activity of these neurons was recorded in the MPC contralateral (right MPC, n = 88) and ipsilateral (left MPC, n = 103) to the stimulated hand of four monkeys performing this somesthetic task. Animals performed the task by pressing with the right hand one of two target switches to indicate whether the speed of probe movement across the skin of the left hand was low or high. Differential responses of MPC neurons occurred during the stimulus and reaction time period. We used an analysis based on signal detection theory to determine whether these differential responses were associated with the animal's decision. According to this analysis, 104 of the 191 neurons (right MPC, n = 48; left MPC, n = 56) coded the categorization of the stimulus speeds (categorical neurons). In a light instruction task, we tested the possibility that the categorical neurons (n = 71) were associated with the intention to press, or with the trajectory of the hand to one of the two target switches used to indicate categorization...Continue Reading

Citations

May 28, 2009·Psychological Research·W Todd MaddoxF Gregory Ashby
Oct 6, 2007·Journal of Computational Neuroscience·Heesoo Kim, Shaowen Bao
Apr 13, 2000·Brain Research. Brain Research Reviews·E J TehovnikP H Schiller
Oct 3, 2002·Behavioural Brain Research·Ranulfo RomoRogelio Luna
Aug 17, 1999·Current Opinion in Neurobiology·R Romo, E Salinas
Jan 1, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·R Dowman, S Schell
Sep 10, 2002·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Ranulfo RomoEmilio Salinas
Apr 3, 2001·Annual Review of Neuroscience·R Romo, E Salinas
Sep 9, 2010·BMC Neuroscience·Wynn LegonW Richard Staines
Mar 9, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Shikha J GoodwinMatthew V Chafee
Oct 18, 2007·Proceedings of the National Academy of Sciences of the United States of America·Luis LemusRanulfo Romo
Sep 17, 2014·Progress in Neurobiology·Germán Mendoza, Hugo Merchant
Nov 6, 2014·Experimental Brain Research·Supriya Ray, Stephen J Heinen
Mar 3, 2015·The European Journal of Neuroscience·Hugo MerchantLuis Prado
Jun 15, 2004·NeuroImage·Jussi NumminenRiitta Hari
Apr 5, 2012·Progress in Neurobiology·Ranulfo Romo, Victor de Lafuente
Apr 1, 2015·Proceedings of the National Academy of Sciences of the United States of America·Manuel AlvarezRanulfo Romo
Aug 15, 2001·Neuron·A BodegårdP E Roland
Mar 22, 2002·Neuron·Adrián HernándezRanulfo Romo
Dec 25, 2003·Vision Research·Jonathan D Victor, Mary M Conte
Dec 27, 2008·Neuron·Moran Furman, Xiao-Jing Wang
Aug 27, 2014·Frontiers in Neuroscience·Hugo MerchantApostolos P Georgopoulos
Mar 6, 2015·PLoS Computational Biology·Jaldert O RomboutsPieter R Roelfsema
Mar 20, 2001·Nature Reviews. Neuroscience·J D Schall
Mar 4, 2003·Nature Reviews. Neuroscience·Ranulfo Romo, Emilio Salinas
Mar 29, 2019·Proceedings of the National Academy of Sciences of the United States of America·Román Rossi-PoolRanulfo Romo
Oct 16, 2001·Journal of Neurophysiology·J R PruettH Burton

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.