PMID: 11909747Mar 23, 2002Paper

Cathelicidins: microbicidal activity, mechanisms of action, and roles in innate immunity

Microbes and Infection
Balaji RamanathanFrank Blecha

Abstract

Antimicrobial peptides are important host-defense molecules of innate immunity. Cathelicidins are a diverse family of potent, rapidly acting and broadly effective antimicrobial peptides, which are produced by a variety of cells. This review examines the classification, antimicrobial spectrum, mechanism of action, and regulation of cathelicidins.

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