Catheter Ablation for "Lone" Atrial Fibrillation: Efficacy and Predictors of Recurrence

Journal of Cardiovascular Electrophysiology
A BuiattiI Deisenhofer

Abstract

Atrial fibrillation in otherwise healthy young patients has been termed "lone" atrial fibrillation (AF). The best treatment choice is still under discussion. The aim of this study was to report on efficacy and safety of catheter ablation. Among 855 patients referred to our center between 2011 and 2013, 76 (9%) met the diagnostic criteria for lone AF (mean age 45 ± 8 years; mean LA diameter 37 ± 4 mm; paroxysmal AF 82%; persistent AF 18%). The primary endpoint was freedom from any atrial tachycardia after the first ablation; the secondary endpoint was freedom from any atrial tachycardia after the last ablation procedure without antiarrhythmic drugs. The primary endpoint occurred in 56 patients (74%) after a mean follow-up time of 444 ± 344 days. The secondary endpoint occurred in 73 patients (96%) after a mean of 1.3 ablations/patient during a follow-up time of 459 ± 366 days. The risk of AF recurrence was not influenced by AF duration or by the type of AF (paroxysmal versus persistent). In a multivariate regression analysis smoking (P = 0.001), first degree atrioventricular block (P = 0.001), and early (< 3 months) AF recurrence (P = 0.001) were independently associated with a higher risk of AF recurrence. Major peri-procedural...Continue Reading

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Citations

Jul 16, 2016·Pacing and Clinical Electrophysiology : PACE·Anna BjörkenheimDritan Poçi
Oct 25, 2016·International Journal of Cardiology·Fabian Sanchis-GomarAlejandro Lucia
May 21, 2019·Cardiology in the Young·Jindong ChenLiang Zhao
Dec 18, 2020·Frontiers in Cardiovascular Medicine·Ramadan GhalebFiorenzo Gaita

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