Catheter Ablation of Ventricular Tachycardia in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia: A Sequential Approach

Journal of the American Heart Association
Shibu MathewFeifan Ouyang

Abstract

Background It has been suggested that endocardial and epicardial ablation of ventricular tachycardia ( VT ) improves outcome in arrhythmogenic right ventricular cardiomyopathy/dysplasia. We investigated our sequential approach for VT ablation in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia in a single center. Methods and Results We included 47 patients (44±16 years) with definite (81%) or borderline (19%) arrhythmogenic right ventricular cardiomyopathy/dysplasia between 1998 and 2016. Our ablation strategy was to target the endocardial substrate. Epicardial ablation was performed in case of acute ablation failure or lack of an endocardial substrate. Single and multiple procedural 1- and 5-year outcome data for the first occurrence of the study end points (sustained VT /ventricular fibrillation, heart transplant, and death after the index procedure, and sustained VT /ventricular fibrillation for multiple procedures) are reported. Eighty-one radiofrequency ablation procedures were performed (mean 1.7 per patient, range 1-4). Forty-five (56%) ablation procedures were performed via an endocardial, 11 (13%) via an epicardial, and 25 (31%) via a combined endo- and epicardial approach. Complete acute success...Continue Reading

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Citations

Jul 29, 2020·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Shibu MathewFeifan Ouyang
Sep 20, 2019·Journal of Cardiovascular Electrophysiology·Ahmed I ElbatranMagdi M Saba
Feb 2, 2021·Herzschrittmachertherapie & Elektrophysiologie·Shibu MathewHarilaos Bogossian
Mar 4, 2021·Medicina·Nicola TarantinoAndrea Natale
Mar 31, 2021·Journal of Cardiovascular Electrophysiology·Daniele Muser, Pasquale Santangeli
Jul 29, 2021·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Shibu MathewFeifan Ouyang

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