Catheter-Related Bloodstream Infection

Current Infectious Disease Reports
D P Calfee, B M Farr


Central venous catheters are associated with the vast majority of nosocomial, catheter-related bloodstream infections (CR-BSI). Despite identification of multiple effective methods for preventing CR-BSI, it remains an important clinical problem. Catheters coated with anti-infective substances, such as chlorhexidine and silver sulfadiazine or rifampin and minocycline, have shown promising results in recent clinical trials, but confirmatory studies by different investigators are still needed. Concern has also been raised about widespread use of clinically important antibiotics on catheter surfaces, which may promote the development of antibiotic resistance. More accurate and cost-effective methods of diagnosing CR-BSI are desirable. Recent studies have evaluated endoluminal brush sampling and differential blood culture growth rates, which may provide acceptable accuracy without requiring removal of long-dwelling catheters, but the accuracy of these techniques needs to be confirmed in other studies.


Jun 9, 1977·The New England Journal of Medicine·D G MakiH W Sarafin
Oct 8, 1992·The New England Journal of Medicine·D K CobbB M Farr
Jan 1, 1990·Journal of Clinical Microbiology·R J SherertzL L Fauerbach
Nov 1, 1989·Journal of Clinical Microbiology·M E VillarinoN Clark
Feb 1, 1989·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·C M Beck-Sague, W R Jarvis
Feb 1, 1988·Revue de l'infirmière·Y Domart
Nov 1, 1988·Annals of Surgery·R H SnyderC J McDermott
Apr 1, 1988·British Journal of Hospital Medicine·A J Coe, D P Coates
Jan 1, 1987·Nephron·S Z TrooskinR S Greco
Feb 21, 1986·JAMA : the Journal of the American Medical Association·R L LuskinS A Kabins
Apr 4, 1974·The New England Journal of Medicine·J A RyanJ E Fischer
Jul 1, 1984·Medicine·O W PressR O Hickman
Jun 1, 1980·The Journal of Infectious Diseases·D J CleriS J Seligman
Dec 1, 1981·American Journal of Surgery·A H GraeveW R Schiller
Sep 1, 1994·Critical Care Medicine·M K O'MalleyR C McComb
Feb 1, 1994·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P AndrivetC Brun-Buisson
May 25, 1994·JAMA : the Journal of the American Medical Association·D PittetR P Wenzel
Feb 1, 1996·The Journal of Infectious Diseases·I RaadG P Bodey
Nov 1, 1995·Antimicrobial Agents and Chemotherapy·I RaadG P Bodey
Mar 1, 1997·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·E TacconelliL Ortona
Apr 1, 1997·Journal of Clinical Microbiology·Y Siegman-IgraB M Farr

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