Cathodic adsorptive stripping square-wave voltammetry of the anti-inflammatory drug meloxicam

Chemical & Pharmaceutical Bulletin
A E RadiA Beltagi

Abstract

The adsorptive behavior of the anti-inflammatory drug meloxicam was studied by cyclic, differentia-pulse and square-wave voltammetry on a hanging mercury drop electrode (HMDE). The drug was accumulated at HMDE and a well-defined stripping peak current was obtained at -1.42 V vs. Ag/AgCl (saturated KCl) electrode in acetate buffer solution (pH 5.0). A voltammetric procedure was developed for the determination of meloxicam using square-wave cathodic adsorptive stripping voltammetry (SW-CASV). The optimum working conditions for the determination of the drug were established. The analysis of meloxicam in human plasma was carried out satisfactorily.

References

Apr 1, 1996·British Journal of Rheumatology·D TürckU Busch
Apr 1, 1996·British Journal of Rheumatology·M DistelJ Fries
Feb 1, 1996·British Journal of Clinical Pharmacology·H NarjesG Nehmiz
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Jun 1, 1997·Seminars in Arthritis and Rheumatism·D E Furst
Mar 16, 2000·Journal of Chromatography. B, Biomedical Sciences and Applications·T VelpandianS K Gupta

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