PMID: 6970783Jan 1, 1981Paper

Cation complexed DNA. A novel class of immunoadsorbents for anti-DNA antibodies

Journal of Immunological Methods
V A DeBari, M A Needle

Abstract

DNA can be precipitated as complexes with metal and organic cations. We have prepared these products using divalent metal cations (Cu2+, Mn2+, Ni2+, Zn2+, and Co2+) and ditetrazolium ions (blue tetrazolium and neotetrazolium). They are effective adsorbents, in vitro, for anti-nDNA antibodies and in reducing the titer of antinuclear antibodies in the sera from patients with autoimmune disease. They selectively adsorb most of the antinuclear components from a mixture of antimitochondrial and antinuclear antibodies.

References

Dec 20, 1979·The New England Journal of Medicine·R LahitaM M Reidenberg
Sep 1, 1978·The Journal of Clinical Investigation·M J Fritzler, E M Tan
Dec 15, 1974·Experientia·D S TermanR Harbeck
Jul 1, 1971·The Journal of Experimental Medicine·D KofflerH G Kunkel
Mar 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·Y MoroiE M Tan
Jan 1, 1980·Journal of Immunological Methods·E Fishbein, D Alarcón-Segovia

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Citations

May 1, 1993·Free Radical Biology & Medicine·K FrenkelE Taioli
Oct 16, 2002·Journal of Immunological Methods·Barbara MouratouJean-Luc Guesdon
Aug 25, 1984·Lancet·D A IsenbergR S Schwartz
Oct 31, 2001·Molecular Immunology·Y J Jang, D Sanford
Oct 8, 1999·Pharmacology & Therapeutics·N B Blatt, G D Glick
Jun 1, 1987·Annals of the Rheumatic Diseases·D A IsenbergA Todd-Pokropek

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