Cationization versus surface activity--the effect on electrospray ionization

European Journal of Mass Spectrometry
Magdalena FrańskaTomasz Kozik

Abstract

Ethoxylated fatty alcohols, C(12)E(1), C(12)E(2), C(18)E(1) and C(18)E(2), were studied by electrospray ionization mass spectrometry (E is the ethoxylene unit OCH(2)CH(2)). For compounds containing two ethoxylene units, which form quite stable adducts with sodium cation, the abundances of [M + Na](+) ions were not affected by alkyl chain, so the hydrophobic effect was not observed. For the compounds containing one ethoxylene unit, forming rather unstable adducts with sodium, the hydrophobic effect was clearly seen since the [C(18)E(1) + Na](+) ion was more abundant than the [C(12)E(1) + Na](+) ion. Two ethoxylene units are not able to form stable adducts with potassium cations, therefore the hydrophobic effect was observed for the [C(12)E(2) + K](+) and [C(18)E(2) + Na](+) ions, the latter being more abundant than the former. For lithium cation adducts with C(12)E(1) and C(18)E(1), the hydrophobic effect was observed, but was less manifested than for sodium cations since lithium adducts are more stable than sodium ones. C(18)E(1) and C(18)E(2) gave more intense signals at higher cone voltage values than C(12)E(1) and C(12)E(2), respectively. However, this is not related to the hydrophobic effect but to the collisions being less...Continue Reading

References

Jul 25, 2000·Analytical Chemistry·N B Cech, C G Enke
May 9, 2002·Mass Spectrometry Reviews·N B Cech, C G Enke
Apr 11, 2003·Journal of the American Society for Mass Spectrometry·Rafał FrańskiOles P Szwajka
Aug 27, 2003·European Journal of Mass Spectrometry·Magdalena FrańskaRafał Frański
Apr 15, 2005·Analytical Chemistry·Jimmy FlarakosPaul Vouros
May 3, 2005·Journal of the American Society for Mass Spectrometry·Jennifer L FrahmMichael J Burke

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Citations

Apr 3, 2008·Rapid Communications in Mass Spectrometry : RCM·Rafał FrańskiBogdan Wyrwas
Nov 15, 2006·Journal of Mass Spectrometry : JMS
Aug 1, 2008·Rapid Communications in Mass Spectrometry : RCM·Rafał FrańskiTomasz Kozik

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