Caudate lobe resection with major hepatectomy for central cholangiocarcinoma: is it of value?

Hepato-gastroenterology
Mohamed Abdel WahabNabieh El-Ghawalby

Abstract

The aim of this study was to evaluate the importance of concomitant caudate lobe resection in the course of major hepatectomy for hilar cholangiocarcinoma. During the period between January 1995 and December 2010, 159 patients were subjected to major hepatectomy with or without total caudate lobe resection at the Gastroenterology Centre, Mansoura University. These patients were divided in two groups: 1) a caudate lobe preservation (CLP) group (79 patients) and 2) a caudate lobe resection (CLR) group (80 patients). All patient data were retrospectively reviewed. This study included 94 men and 65 women with a mean age of 53.5±0 years without operative mortality. No differences were observed between groups regarding operative time, blood loss or the development of any individual postoperative complication. There were 23 (28.8%) margin-positive resections in the CLR group and 49 (62%) margin-positive resections in the CLP group (p≤0.001). Recurrence was confirmed in 53 (67.1%) and in 41(51.3%) patients in the CLP and CLR groups, respectively (p=0.031). The median survival of the CLR group was 36 months with a 5-year survival rate of 28%, while the median survival of the CLP group was 22 months with a 5-year survival rate of 5% (p≤0...Continue Reading

Citations

Jan 16, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Traian DumitrascuIrinel Popescu
Aug 16, 2014·American Journal of Surgery·Patryk Kambakamba, Michelle L DeOliveira
Jun 10, 2014·International Journal of Surgery·Mohamed AbdelwahabKhaleed Zalata
May 21, 2014·Langenbeck's Archives of Surgery·Irinel Popescu, Traian Dumitrascu
Oct 12, 2015·Journal of the American College of Surgeons·Bas Groot KoerkampThomas M van Gulik
Jul 15, 2015·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·John C MansourJean-Nicolas Vauthey
Mar 20, 2015·Journal of Hepato-biliary-pancreatic Sciences·Masaru MiyazakiTadahiro Takada
Mar 29, 2016·The Surgical Clinics of North America·Hermien HartogBas Groot Koerkamp
Jun 23, 2016·Gynecologic Oncology Research and Practice·Neville F Hacker, Archana Rao
Jul 1, 2016·World Journal of Gastrointestinal Surgery·Mohamed Abd ElWahabTarek Salah
Apr 17, 2018·Minerva chirurgica·Enrico PinottiLuca Gianotti
Sep 29, 2017·The Journal of Medical Investigation : JMI·Masato YoshikawaMitsuo Shimada
Aug 31, 2018·Gastroenterology Research and Practice·Madalina Maria BlagaTraian Dumitrascu

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