Causal Evidence for a Neural Component of Spatially Global Hemodynamic Signals

Neuron
Kathrin Müsch, Christopher J Honey

Abstract

In this issue of Neuron, Turchi et al. (2018) reversibly inactivate the basal forebrain to show that this region magnifies global neocortical signal fluctuations without altering the topography of canonical resting-state networks. Thus, spatially diffuse signals measurable via functional neuroimaging may track large-scale neuromodulatory state changes in the primate brain.

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