Causal mechanisms of subjective cognitive dysfunction in schizophrenic and depressed patients

The Journal of Nervous and Mental Disease
R J van den Bosch, R P Rombouts

Abstract

We examined causal mechanisms of subjective cognitive (dis)abilities in schizophrenic and depressed patients, and in patient and normal control groups. This exploratory study included objective cognitive performance (Continuous Performance Task) as well as mood and mental effort ratings. Self-report of cognitive dysfunction in patients was not correlated with objective cognitive deficits. Correlational patterns differed between groups. Our findings in schizophrenic and depressed patients point to different causal mechanisms of their subjective cognitive malaise, despite similar subjective ratings. Depressed patients associate high mental effort during task performance with a reduced cognitive efficacy, whereas schizophrenic patients associate high effort with cognitive symptoms like distractibility and overload.

References

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Citations

Dec 31, 2002·Psychoneuroendocrinology·S Kasper, E Resinger
Sep 10, 1999·Schizophrenia Research·E A HolthausenR J Van den Bosch
Feb 13, 2013·Applied Neuropsychology. Adult·Linda A SchooAlbert Postma
Jun 15, 2007·Schizophrenia Bulletin·Richard S E Keefe, Wayne S Fenton
Jan 18, 2008·Schizophrenia Bulletin·Alice Medalia, Julie Thysen
Mar 22, 2005·The Australian and New Zealand Journal of Psychiatry·Geoff WaghornRobert King
Apr 24, 2002·Journal of Neurology, Neurosurgery, and Psychiatry·J R FannR S Thompson
Apr 1, 2010·Revista de psiquiatrí́a y salud mental·Rosario Bengochea SecoAna Alvarez Soltero
May 7, 2008·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Richard S E Keefe
Oct 4, 2006·Journal of Psychiatric Research·Christopher R BowiePhilip D Harvey
Sep 13, 2005·Schizophrenia Research·Marielle GorissenBen Schmand
Sep 29, 2011·Schizophrenia Research·B González-SuárezP J McKenna
Dec 19, 2013·Journal of Clinical and Experimental Neuropsychology·James GilleenAnthony S David
Dec 20, 2017·The Journal of Nervous and Mental Disease·Tim BastiaensMarc De Hert

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