Causal relationships among factors associated with cancer-related fatigue

European Journal of Oncology Nursing : the Official Journal of European Oncology Nursing Society
YoungMin SeoWhaSook Seo

Abstract

This study was conducted to develop and verify a comprehensive model, which illustrates the dynamic causal relationships between fatigue and its associated factors in cancer patients. The subjects were 110 in- or out-patients with various types of cancer being treated at a University Hospital, Incheon, South Korea. The comprehensive model consists of physical distress, sleep-related, physiologic, psychological distress, physical performance, and exercise factors. Psychological distress had a significant direct effect on physical distress, and 81% of the variance in physical distress was explained by psychological distress. While psychological distress showed to have a significant total effect (the sum of direct effects of psychological distress and indirect effects through its relationship with physical distress) on fatigue, it was not found to have a significant direct effect on fatigue. Only exercise had a significant direct effect on fatigue and 70% of fatigue variance was explained by exercise alone. All remaining factors were not found to have significant direct effects on fatigue. The hypothetical model was well suited to explain cancer-related fatigue. Our result indicates that psychological distress should be relieved i...Continue Reading

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