Cause of death: suicide

Journal of Molecular and Cellular Cardiology
Jan KajsturaAnnarosa Leri

Abstract

In the last decade, apoptosis has gained recognition as an important event determining the structure and function of the myocardium. The purpose of this review is to provide insights into the mechanisms controlling programmed cell death of myocytes. In this regard, the role of the local renin-angiotensin system and oxidative stress is emphasized. Moreover, the effect of cell death on ventricular remodeling and performance is analyzed. The impact of the identification of apoptosis in the heart on the current view of myocardium as a dynamic organ is discussed.

Citations

Apr 9, 2008·Physiological Reviews·Elizabeth Murphy, Charles Steenbergen
Oct 9, 2012·American Journal of Physiology. Heart and Circulatory Physiology·Christopher R DanielsKrishna Singh
May 31, 2008·European Heart Journal·Stefan RuppStefanie Dimmeler
Jul 22, 2011·Journal of Signal Transduction·Parthiv AminKrishna Singh
Mar 21, 2012·Antioxidants & Redox Signaling·Daniela Zablocki, Junichi Sadoshima
Apr 17, 2012·Autonomic Neuroscience : Basic & Clinical·E Marie SoutherlandJeffrey L Ardell
Jan 24, 2012·Journal of Molecular and Cellular Cardiology·Chaoming ZhouEdwin S Levitan
Jun 24, 2008·Progress in Neuro-psychopharmacology & Biological Psychiatry·Maurizio PompiliPaolo Girardi
Mar 8, 2008·Journal of Cardiac Failure·Daniele Gonçalves BezerraCarlos Alberto Mandarim-de-Lacerda
Apr 12, 2008·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Louis Maximilian Buja, Deborah Vela
May 16, 2008·Molecular Nutrition & Food Research·Shang-Ming HuangGow-Chin Yen
Apr 28, 2007·Circulation Research·Sean M Davidson, Michael R Duchen
Sep 7, 2007·Medicine and Science in Sports and Exercise·Scott K PowersAndreas N Kavazis
Dec 16, 2011·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Julia L Cook, Richard N Re

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