Causes and mechanisms of acid-base and electrolyte abnormalities in cancer patients

European Journal of Internal Medicine
George MiltiadousMoses Elisaf

Abstract

Patients with cancer frequently exhibit acid-base and electrolyte disturbances that complicate their management and prolong their hospitalization. The mechanisms encountered for these abnormalities are multifactorial in origin. Both the underlying disease and the therapeutic interventions can contribute to the development of these disturbances. An understanding of the mechanisms involved in their pathogenesis is of paramount importance for their prevention and treatment in cancer patients. This article briefly reviews the causes and the pathophysiology of acid-base and electrolyte abnormalities observed in cancer patients.

References

Aug 1, 1992·The American Journal of Medicine·B M WallC R Cooke
Apr 1, 1988·Southern Medical Journal·G C DoolittleD C Bodensteiner
May 1, 1983·European Journal of Cancer & Clinical Oncology·J P SculierJ Klastersky
Mar 28, 1981·British Medical Journal·P C AdamsA Parnham
Aug 1, 1995·Journal of Internal Medicine·J B SørensenH H Hansen
Jan 1, 1997·American Journal of Nephrology·M S ElisafK C Siamopoulos
Sep 1, 1997·The Journal of Urology·D M Reese, P J Rosen
Dec 10, 1999·American Journal of Hematology·H J MilionisM S Elisaf
Jan 8, 2000·Hematology/oncology Clinics of North America·M Q Lacy, M A Gertz
Apr 25, 2003·The New England Journal of Medicine·Thomas O Carpenter
Jul 18, 2003·Medical and Pediatric Oncology·Marshall P Goren
Oct 31, 2003·Oncology·J Klastersky
Mar 3, 2004·Journal of Cellular Biochemistry·Evan T Keller, Julie Brown
Jun 26, 2004·Journal of Pediatric Hematology/oncology·Ran D Goldman, Gideon Koren
Jan 28, 2005·The New England Journal of Medicine·Andrew F Stewart
May 3, 2005·Cytokine & Growth Factor Reviews·Xijie Yu, Kenneth E White
May 21, 2005·Annals of Medicine·Norbert H LameireClaudio Ronco
May 25, 2005·Contributions to Nephrology·Takashi TaguchiMohammed S Razzaque
Jun 11, 2005·Cancer Chemotherapy and Pharmacology·H LajerT E N Jonassen
Nov 30, 2005·European Journal of Haematology·Theodosios D FilippatosMoses S Elisaf

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Citations

May 28, 2013·BMC Cancer·Wahyu WulaningsihMieke Van Hemelrijck
Mar 5, 2016·European Journal of Pharmacology·George LiamisMoses S Elisaf
Jun 29, 2011·Hematological Oncology·Yo Han AhnHee Gyung Kang
Dec 15, 2010·Seminars in Nephrology·Norbert LameireRaymond Vanholder
Jun 14, 2016·Environmental Research·Jerome NriaguBasem Shomar
Feb 16, 2021·Frontiers in Physiology·Yiheng YangYunlong Xia
Apr 25, 2009·Current Opinion in Endocrinology, Diabetes, and Obesity

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