PMID: 9530448Apr 8, 1998Paper

Causes of failure and dangers in the use of motor driven infusion pumps. Accidental closure of the infusion system

Der Anaesthesist
D HeiseD Kettler

Abstract

Syringe drivers are used in anaesthetics, intensive care and emergency medicine to deliver small volumes of highly potent drugs with continuous, constant and reproducible flow. For early recognition of interruptions of the drug delivery caused by occlusion of the infusion system, an alarm is triggered as soon as the system pressure exceeds a certain limit. The sensitivity of this alarm depends on the flow rate, type-specific cut-off pressure and the elastic parameters of the infusion system. The sudden release of pressure built up in the system after occlusion occurred can cause delivery of an uncontrolled drug bolus and hence an additional hazard. Six syringe drivers that are widely used in clinical practice were tested for alarm delay and bolus delivery in the event of an occlusion in the system. First, the alarm pressures at flow rates of 10, 50 and 100 ml/h were measured. Then the alarm delay time and bolus volumes post-occlusion were assessed, using a basic infusion system (syringe + single infusion set). Finally, several alterations to the system like extension, tap battery with germ filters or branching were made and their impact on alarm delay and bolus volume measured. Because of the great differences in alarm pressure...Continue Reading

Citations

Sep 4, 2008·Critical Care Medicine·Roy IlanEdward E Etchells
Jan 5, 2005·Diabetes Technology & Therapeutics·Meghan SimmonsBurton Sage

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