PMID: 9661284Jul 14, 1998Paper

Cd2+ effects on respiration and swelling of rat liver mitochondria were modified by monovalent cations

Journal of Inorganic Biochemistry
Sergey M KorotkovVadim V Glazunov

Abstract

Changes in Cd2+ effects on respiration of succinate-energized rat liver mitochondria were studied after replacement of 100 mM KCl in an incubation medium by equimolar amounts of NaCl or LiCl, or by 200 mM sucrose. In KCl medium, 2.5-10 microM Cd2+ decreased the state 3 and 2,4-dinitrophenol (DNP)-stimulated respiration of mitochondria, and increased their respiration in the state 4, however, 10-40 microM Cd2+ diminished the state 4 respiration. Compared to the experiments with KCl medium, it was demonstrated that Cd2+ effects on the mitochondrial respiration was increased in NaCl medium, decreased in sucrose medium, and unchanged in LiCl medium, except that 10-25 microM Cd2+ decreased the state 4 respiration of mitochondria in the same way as in the NaCl medium. Cd2+ (20 microM) stimulated an extensive swelling of nonenergized mitochondria incubated in 125 mM nitrate media, the effect being increased in the series of Li < Na < K < NH4. Swelling of succinate-energized mitochondria incubated in K-acetate medium was additionally stimulated by 10 microM Cd2+. The initially low swelling of succinate-energized mitochondria in the KCl medium increased with increase in Cd2+ concentrations in this medium. Differences found in the Cd2+ e...Continue Reading

References

Jan 31, 1976·Molecular and Cellular Biochemistry·G P Brierley
Apr 1, 1978·Journal of Bioenergetics and Biomembranes·K A Webster, J R Bronk
Jan 12, 1976·Biochemical and Biophysical Research Communications·G P Brierley, M Jurkowitz
Feb 1, 1977·Journal of Bioenergetics and Biomembranes·A Gómez-Puyou, M Tuena de Gómez-Puyou
Dec 1, 1978·Journal of Bioenergetics and Biomembranes·A Fonyó
Feb 22, 1990·European Journal of Biochemistry·P BernardiG F Azzone
Jan 1, 1968·Canadian Journal of Biochemistry·R Cereijo-Santaló
Jan 4, 1972·Biochemistry·A Gómez-PuyouE Chávez
Jun 1, 1969·European Journal of Biochemistry·P Mitchell, J Moyle
Nov 2, 1984·European Journal of Biochemistry·B K RasheedD R Sanadi
Nov 30, 1981·Biochemical and Biophysical Research Communications·E J Harris, M B Cooper
Sep 16, 1980·Biochemical and Biophysical Research Communications·E Lam, S I Tu
Oct 1, 1994·Journal of Bioenergetics and Biomembranes·G P BrierleyD W Jung
Jul 1, 1994·Toxicology and Applied Pharmacology·C M PalmeiraV M Madeira
Mar 11, 1994·Toxicology·B el AzzouziY Thomas
Dec 1, 1993·Chemico-biological Interactions·S Miccadei, A Floridi
May 1, 1958·Biochimica Et Biophysica Acta·H TEDESCHI, D L HARRIS
Jan 15, 1963·Biochimica Et Biophysica Acta·J L GAMBLE
Apr 23, 1965·Biochemical and Biophysical Research Communications·Z DRAHOTA, A L LEHNINGER

❮ Previous
Next ❯

Citations

Feb 24, 2001·Archives of Biochemistry and Biophysics·E CasalinoC Landriscina
Jul 25, 2009·Journal of Bioenergetics and Biomembranes·Sergey M Korotkov
Mar 23, 2011·Journal of Bioenergetics and Biomembranes·Sergey M Korotkov, Nils-Erik L Saris
Sep 24, 2011·Zhurnal evoliutsionnoĭ biokhimii i fiziologii·I V ShemarovaV P Nesterov
Jan 28, 2014·Zhurnal evoliutsionnoĭ biokhimii i fiziologii·I V ShemarovaV P Nesterov
Oct 16, 2007·Doklady. Biochemistry and Biophysics·S M KorotkovN N Ryabchikov
Apr 13, 2010·Doklady. Biochemistry and Biophysics·S M KorotkovI V Brailovskaya
Feb 3, 2016·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Sergey M KorotkovNils-Erik L Saris
Dec 15, 2010·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Elena A BelyaevaNils-Erik Saris
Aug 27, 2009·Mitochondrion·Giuseppe CanninoAnna Maria Rinaldi
Jan 18, 2014·Journal of Biochemical and Molecular Toxicology·Sergey M KorotkovViktor V Furaev
Aug 18, 2004·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Claudia ManzlReinhard Dallinger
Jun 19, 2008·Journal of Biochemical and Molecular Toxicology·Sergey M KorotkovOlga V Yagodina
Apr 26, 2015·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Sergey M KorotkovIrina V Brailovskaya
Apr 25, 2008·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Anna V IvaninaInna M Sokolova
Apr 12, 2007·Journal of Biochemical and Molecular Toxicology·Sergey M KorotkovOlga V Yagodina
Jan 1, 2004·Toxicology Mechanisms and Methods·Wing-Kee LeeFrank Thévenod
Dec 18, 2020·Frontiers in Cell and Developmental Biology·Jacopo Junio Valerio BrancaMatteo Becatti
Jul 9, 2021·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Sergey M Korotkov

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.