CD5 helps aspiring regulatory T cells ward off unwelcome cytokine advances

Immunity
Amy C Palin, Paul E Love

Abstract

The role of co-receptor molecules in the generation of inducible regulatory T cells (iTregs) remains incompletely defined. In this issue of Immunity, Henderson et al. (2015) show that CD5 regulates iTreg cell induction by rendering emerging iTreg cells refractory to signals mediated by effector-differentiating cytokines.

Citations

Apr 28, 2018·International Journal of Molecular Sciences·Claudia M Tellez FreitasK Scott Weber
Mar 16, 2017·Molecular and Cellular Biology·Johannes Breuning, Marion H Brown
Aug 28, 2016·Oncotarget·Hilmar QuentmeierHans G Drexler
Nov 9, 2017·PLoS Biology·Jiyoung OhDong-Ming Su

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