CD73 and adhesion of B-cells to follicular dendritic cells

Leukemia & Lymphoma
L Airas

Abstract

CD73, otherwise known as ecto-5'-nucleotidase, is a lymphocyte maturation marker which is involved in intracellular signalling, lymphocyte proliferation and activation. In addition, we have demonstrated that CD73 is involved in mediating lymphocyte binding to in vitro cultured endothelial cells and in controlling adhesion between freshly isolated germinal center B-cells and follicular dendritic cells (FDC). In secondary lymphoid tissues, CD73 is expressed on FDC in the light zone of the germinal center as well as on small, resting mantle zone B-cells but not on B-cells within germinal centers. In this review article, the potential role of CD73 in controlling B-cell-FDC interactions and B-cell maturation will be discussed.

References

Jul 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·N L EdwardsI H Fox
Apr 1, 1992·Immunological Reviews·M H Kosco, D Gray
Jul 15, 1992·The Biochemical Journal·H Zimmermann
Jan 1, 1992·Immunology Today·Y J LiuI C MacLennan
Jan 1, 1991·Immunology Today·P J Robinson
Jan 1, 1991·Annual Review of Immunology·E A Clark, P J Lane
Jan 1, 1989·Biological Chemistry Hoppe-Seyler·S Buschette-Brambrink, W Gutensohn
Sep 15, 1989·Biochimica Et Biophysica Acta·U StochajH G Mannherz
Dec 21, 1989·Nature·Y J LiuI C MacLennan
Jun 1, 1995·The European Journal of Neuroscience·A Heilbronn, H Zimmermann
Apr 1, 1995·Cellular Immunology·W GutensohnL F Thompson
Jan 1, 1994·Annual Review of Immunology·I C MacLennan
Feb 3, 1994·Nature·E A Clark, J A Ledbetter
Apr 26, 1994·Proceedings of the National Academy of Sciences of the United States of America·M W CarrT A Springer
Jan 1, 1993·Annual Review of Immunology·D Gray
Jan 1, 1997·European Journal of Immunology·A M ArvilommiS Jalkanen

❮ Previous
Next ❯

Citations

Apr 12, 2008·Purinergic Signalling·Sean P ColganLinda F Thompson
May 5, 2012·Purinergic Signalling·Herbert ZimmermannNorbert Sträter
Apr 23, 2013·Trends in Molecular Medicine·Luca AntonioliGyörgy Haskó
Aug 15, 2014·Biomedical Journal·Ana Carolina MorandiniRobson Coutinho-Silva
Jul 28, 2009·Mechanisms of Ageing and Development·Thorsten PetersKarin Scharffetter-Kochanek
Mar 17, 2007·Life Sciences·Fernanda Cenci VuadenCarla Denise Bonan
Dec 1, 2010·European Journal of Pharmacology·Fernanda Cenci VuadenCarla Denise Bonan
Aug 22, 2013·Proceedings of the National Academy of Sciences of the United States of America·Paul A BeavisPhillip K Darcy
Mar 5, 2017·Immunological Reviews·Bertrand AllardJohn Stagg
Nov 8, 2012·Journal of Biomedicine & Biotechnology·François GhiringhelliCédric Rébé
Jan 5, 2019·Cancer Immunology, Immunotherapy : CII·Amedeo SciarraLaurence de Leval
Jul 16, 2021·Life Sciences·Elham BaghbaniBehzad Baradaran

❮ Previous
Next ❯

Related Concepts

Related Feeds

CNS Lymphoma

In CNS lymphoma, cancerous cells from lymph tissues or other parts of the body form tumors in the brain and/or spinal cord. Here is the latest research on this rare non-Hodgkin lymphoma.

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.