CDK12 Changes Telling in Prostate Cancer

Cancer Discovery

Abstract

A recent study established that patients with metastatic castration-resistant prostate cancer who had mutations that inactivated both CDK12 alleles also exhibited other genetic changes. Results of a small, related study suggest these genetic changes may make tumors more responsive to PD-1 inhibitors.

Citations

Nov 10, 2018·Transcription·Matthew D GalbraithJoaquín M Espinosa

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