CDK4/6 inhibitors in the treatment of patients with breast cancer: summary of a multidisciplinary round-table discussion.

ESMO Open
Matthias PreusserChristoph C Zielinski

Abstract

This article is the result of a round-table discussion organised by ESMO Open in Vienna in December 2017. Its purpose is to discuss the background and advances in the evidence regarding cyclin-dependent kinase 4/6 inhibitors (palbociclib, ribociclib and abemaciclib) in the treatment of metastatic and early-stage breast cancer and to explore what the key open research questions are and next steps should be.

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Citations

Apr 12, 2020·Journal of Cellular and Molecular Medicine·Yingxiao CaoYanhui Qi
Aug 25, 2020·Archives of Gynecology and Obstetrics·Daniel Martin Klotz, Pauline Wimberger
Dec 13, 2019·Proceedings of the National Academy of Sciences of the United States of America·Xiaoyong FuRachel Schiff
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Jan 17, 2021·Journal of Cellular and Molecular Medicine·Xiaotong ZhangChuize Kong
Aug 28, 2019·Oncology Reviews·Amrallah A MohammedFifi Mostafa Elsayed
Sep 10, 2021·JAMA Oncology·Tal SellaOtto Metzger-Filho

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Methods Mentioned

BETA
biopsy
transgenic
xenografts

Clinical Trials Mentioned

NCT02273973
NCT03065621
NCT02513394
NCT03155997
NCT01864746
NCT02530424
NCT02947685
NCT02448420
NCT02675231
NCT02657343

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