PMID: 11918632Mar 29, 2002Paper

cDNA cloning of the polymeric immunoglobulin receptor of the marsupial Macropus eugenii (tammar wallaby)

European Journal of Immunogenetics : Official Journal of the British Society for Histocompatibility and Immunogenetics
C L TaylorE M Deane

Abstract

cDNA encoding a marsupial polymeric immunoglobulin receptor (pIgR) was isolated from Macropus eugenii (tammar wallaby) mammary lymph node primarily by reverse transcriptase coupled polymerase chain reaction (RT-PCR) and rapid amplification of cDNA ends (RACE) PCR. This resulted in a 5' truncated clone and, in order to obtain the full-length sequence, genomic walking PCR was utilized. The complete sequence consists of 2696 bp of cDNA and encodes a predicted polypeptide of 732 amino acids. The wallaby sequence is highly conserved in relation to the only other reported marsupial pIgR sequence, that of Trichosurus vulpecula (brushtail possum), having a nucleotide identity of 86.7% and a deduced amino acid identity of 79.9%. The wallaby nucleotide sequence also has a moderate degree of similarity with the pIgR sequences of eutherian mammals, being most similar to that of the rat, with an identity of 63.1%. At the amino acid level, in comparison to eutherian sequences, the wallaby pIgR is most similar to that of humans with an identity of 52.6%. pIgR phylogenetic trees were constructed for tammar wallaby, brushtail possum and several eutherian mammal cDNA and deduced amino acid sequences. In both DNA and protein analyses, the eutheri...Continue Reading

References

Jul 1, 1992·The American Journal of Psychiatry·J A Lazarus
Jan 1, 1990·Reproduction, Fertility, and Development·E M DeaneM B Renfree
Jan 1, 1985·Annual Review of Immunology·M E Koshland
Apr 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·W R Pearson, D J Lipman
Jul 1, 1986·American Journal of Reproductive Immunology and Microbiology : AJRIM·N K SamplesW H Stone
Aug 1, 1971·Developmental Biology·J J Marchalonis
Dec 1, 1969·The Journal of Experimental Medicine·G A Leslie, L W Clem
Oct 26, 1981·Clinica Chimica Acta; International Journal of Clinical Chemistry·Y IshiguroT Ito
Jan 1, 1995·Developmental and Comparative Immunology·G W Warr
Feb 1, 1994·Comparative Immunology, Microbiology and Infectious Diseases·R D Jurd
Jan 1, 1995·Advances in Experimental Medicine and Biology·E Fallgren-GebauerN Hilschmann
Aug 1, 1996·Computer Applications in the Biosciences : CABIOS·R D Page
Jan 1, 1997·Reproduction, Fertility, and Development·P E Cowan, C H Tyndale-Biscoe
Apr 28, 2000·Developmental and Comparative Immunology·R D Miller, K Belov
Oct 1, 1975·Journal of Religion and Health·J A Bostrom

❮ Previous
Next ❯

Citations

Oct 5, 2002·Journal of Anatomy·Julie M Old, Elizabeth M Deane
Jan 19, 2005·The FEBS Journal·Russell V BaudinetteJohn H Bowie
Jul 16, 2009·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Li-Na FengHao-Ran Lin
Apr 20, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Koji HamuroYuzuru Suzuki

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.