PMID: 6170981Aug 1, 1981Paper

cDNA sequence of a new chicken embryonic rho-globin

Proceedings of the National Academy of Sciences of the United States of America
I B Roninson, V M Ingram

Abstract

In order to use specific DNA probes for the study of developmentally regulated gene expression, we have prepared cDNA clones corresponding to chicken embryonic globins by inserting cDNA.mRNA hybrids into the Pst I site of the plasmid pBR322 by using poly(dG) and poly(dC) linkers. The nucleotide sequence of the insert of one clone, representing a nearly full-length copy of an embryonic beta-like globin cDNA, has been determined. The amino acid sequence of the globin encoded by this insert is identical to the sequence of embryonic rho-globin, except for four amino acid residues near the carboxy terminus. Comparison of mRNA sequences of the embryonic and adult chicken beta-globins indicates the presence of extensive deletions in the 3' untranslated region of the embryonic gene.

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Citations

May 1, 1986·Molecular & General Genetics : MGG·A KretsovaliK Scherrer
Jul 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·R L Eckert, H Green
Jan 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·B W Glickman, L S Ripley
Nov 25, 1982·Nucleic Acids Research·D WoodA J Jeffreys
Nov 11, 1986·Nucleic Acids Research·T C SantiagoA J Brown
May 27, 2016·Epigenetics & Chromatin·Sanzida JahanJames R Davie

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