Celiac Disease and Nonceliac Gluten Sensitivity

Pediatric Clinics of North America
Runa D Watkins, Shamila Zawahir

Abstract

Gluten-related disorders include celiac disease (CD), wheat allergy, and nonceliac gluten sensitivity. CD is an autoimmune enteropathy caused by damage to small intestinal mucosa when gluten is ingested in genetically susceptible individuals. Currently, the only available treatment of CD is gluten-free diet. Several potential treatments are being researched. Wheat allergy is a hypersensitivity reaction caused by IgE-mediated and/or non-IgE-mediated immune response, and can involve the gastrointestinal tract, skin, or respiratory tract. Nonceliac gluten sensitivity is one of a variety of immunologic, morphologic, or symptomatic manifestations precipitated by ingestion of gluten in individuals in whom CD and wheat allergy are excluded.

Citations

Apr 6, 2018·Virchows Archiv : an International Journal of Pathology·Barbara ZaniniChiara Ricci
Feb 13, 2019·Minerva gastroenterologica e dietologica·Alessandro AdrianiRinaldo Pellicano
Jan 10, 2018·European Journal of Gastroenterology & Hepatology·John W BlackettBenjamin Lebwohl
Aug 11, 2018·Virchows Archiv : an International Journal of Pathology·Ayca KirmiziArzu Ensari

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